Nanotechnology Projects at RIT
DNA Sensors
The detection of a single specific DNA molecule fragment will allow for the identification of bacteria and viruses that could be harmful if not detected quickly. DNA probes attached to the sensor electrodes have a specific molecular sequence that results in a billion to one or better probability that any DNA that hybridizes with the probe is the DNA to be detected. The DNA is coated with a metal, resulting in a large decrease in the measured electrical resistance between the sensor electrodes. Thus the electrical detection of a specific single DNA molecule fragment is very easy.
The picture shows two metal lines 1 micrometer apart with a few DNA bridges coated with silver. The measured electrical resistance between the metal conductors dropped from infinity to 2 thousand ohms, making electrical readout of the detection of a single DNA very simple.
This project is led by Dr. Lynn Fuller in collaboration with Integrated Nano-Technologies (INT). For more information on this project click here.